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PCRRT and ICONIC Advances in Critical Care Pediatric Nephrology Textbook

On the occasion of #WorldKidneyDay , we are happy to announce ‘PCRRT and ICONIC Advances in Critical Care Pediatric Nephrology Textbook’ with Springer’s Publisher. It shall be a regular feature dealing with newer updates in the field. The current edition deals with Point of Care Ultrasound in Children with AKI #POCUS and Biomarkers. The book

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Cerebral venous sinus thrombosis in pediatric nephrotic syndrome

A 2-year-old girl presented to the emergency room with recurrent seizures. The child had been diagnosed with nephrotic syndrome in the previous 2 weeks (serum albumin, 1.5 g/dl; serum creatinine, 0.4 mg/dl) and had been convulsing on and off since the week before presentation. Oral prednisolone (2 mg/kg per day) had been started for 2

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Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome

Children with nephrotic syndrome are vulnerable to developing infections due to a state of relative immunodeficiency, malnourishment, and use of immunosuppression. Case characteristics: We herein report the case of a 3-year-old child with steroid-dependent nephrotic syndrome who presented to us with fever of unknown origin. Observation: The child was found to have an atypical mixed

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Kidney Replacement Therapy in COVID-19 Induced Kidney Failure and Septic Shock: A Pediatric Continuous Renal Replacement Therapy [PCRRT] Position on Emergency Preparedness With Resource Allocation

The recent worldwide pandemic of COVID-19 has had a detrimental worldwide impact on people of all ages. Although data from China and the United States indicate that pediatric cases often have a mild course and are less severe in comparison to adults, there have been several cases of kidney failure and multisystem inflammatory syndrome reported.

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Association of pulse pressure, pulse pressure index, and ambulatory arterial stiffness index with kidney function in a cross-sectional pediatric chronic kidney disease cohort from the CKiD study

The morbidity and mortality of adult and pediatric chronic kidney disease (CKD) and end‐stage renal disease (ESRD) populations are mainly driven by cardiovascular disease (CVD). Improving CVD outcomes focuses on risk assessment of factors including diastolic blood pressure (DBP), systolic blood pressure (SBP), left ventricular mass index (LVMI), pulse pressure (PP), and pulse pressure index

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Consensus guidelines for management of hyperammonaemia in paediatric patients receiving continuous kidney replacement therapy

Hyperammonaemia in children can lead to grave consequences in the form of cerebral oedema, severe neurological impairment and even death. In infants and children, common causes of hyperammonaemia include urea cycle disorders or organic acidaemias. Few studies have assessed the role of extracorporeal therapies in the management of hyperammonaemia in neonates and children. Moreover, consensus

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Neonatal Acute Kidney Injury: A Survey of Perceptions and Management Strategies Amongst Pediatricians and Neonatologists

Neonatal Acute Kidney Injury (AKI) occurs in 40-70% of critically ill newborn infants and is independently associated with increased morbidity and mortality. Understanding the practice patterns of physicians (neonatologists and pediatricians), caring for neonates in India is important to optimize care and outcomes in neonatal AKI. The aim of this study was to identify differences

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Renal Replacement Therapy in Pediatric Acute Kidney Injury

Acute kidney injury (AKI) is common in critically ill children and affects nearly 30–40% of patients admitted to the pediatric intensive care unit (ICU). Even with technological advances in critical care and dialysis, there is a high mortality rate of 66.8% to 90% in ICU patients. Renal replacement therapy (RRT) is often performed to treat

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Pediatric Continuous Renal Replacement Therapy (PCRRT) Expert Committee Recommendation on Prescribing Prolonged Intermittent Renal Replacement Therapy (PIRRT) in Critically Ill Children

Introduction Recently, prolonged intermittent renal replacement therapies (PIRRT) have emerged as cost‐effective alternatives to conventional CRRT and their use in the pediatric population has started to become more prominent. However, there is a lack of consensus guidelines on the use of PIRRT in pediatric patients in an intensive care setting. Methods A literature search was

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What is nephrotic syndrome and what causes it?

Nephrotic syndrome is disease of the kidneys where the filtering system made of functional units called the nephrons, gets damaged. This is the name given to the collection of findings which develop as a result of such a damage. When the filtering system gets damaged, the kidney tends to filter substances which it usually doesn’t,

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