The impact of fluid balance on outcomes in premature neonates: a report from the AWAKEN study group.

This study evaluated the epidemiology of fluid balance (FB) over the first postnatal week and its impact on outcomes in a multi-center cohort of premature neonates from the AWAKEN study. Positive peak Fluid balance [FB] during the first postnatal week and more positive FB on postnatal day 7 were independently associated with mechanical ventilation [MV] at postnatal day 7. Those with a negative FB at postnatal day 7 were less likely to require MV.


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