Persistent hypertension in adulthood is a leading cause of end-stage renal disease (ESRD). Whether lower blood pressure (BP) values, in the range of prehypertension, are also associated with future occurrence of ESRD is unclear. A recent study published in Journal of Hypertension clearly shows that asymptomatic, healthy adolescents with prehypertension have a 32% increased risk
Current issue of CJASN has an excellent review on Nephrotic syndrome written by Dr Emma and his team. It’s a must read for all pediatricians and fellows in nephrology! Minimal change disease (MCD) is a major cause of idiopathic nephrotic syndrome (NS), characterized by intense proteinuria leading to edema and intravascular volume depletion. Image Source
An excellent study from CJASN, Japan published today shows the frequencies of child proteinuria defined as ≥1+ urinary protein were 1.7% in the current smoking group, 1.6% in the past smoking group, and 1.3% in the nonsmoking group. A point to be remembered in infants presenting with proteinuria.
Non-invasive imaging cannot replace formal angiography in the diagnosis of renovascular hypertension
An excellent study published in Pediatric Nephrology journal today from the Great Ormond Street Hospital, UK, shows that the sensitivity of MRA and CTA is still too low to reliably rule out renovascular disease in children with a strong suspicion of this diagnosis. DSA remains the gold standard to diagnose renovascular hypertension and is recommended
Just now saw a child from far away in India, with this MCU showing clearly posterior urethral valves, and now the child is in chronic kidney disease stage V, and requires a transplant. As doctors, we all should spread this message, to diagnose this early and treat it early too fpr better future of these kids!
The results of the Award/ Oral/ Poster presentations for the 28th Annual Conference of Indian Society of Pediatric Nephrology are now out. Please check this attachment here. I shall be speaking on Feasibility & Tolerability of SLED [Sustained Low Efficiency Dialysis] in children.
A recent study from Egypt shows Serum NT-pro BNP levels strongly correlated with LV echocardiographic parameters in patients with ESRD. Despite the high concentrations of NT-pro BNP in all dialysis children, its levels can be used as a diagnostic marker of LV dysfunction by using higher cutoff values. A postdialysis cutoff value of 630 ng/L could
Current Issue of Saudi Journal of Kidney Disease & Transplantation has an excellent paper on Pediatric AKI from Srinagar, India. The incidence of pAKI in general was 0.8%, whereas it was 4% in critically ill children and 0.5% in general ward admissions implying an eight-fold increased risk of pAKI in critically ill patients.
Today, our colleagues from PGIMER Chandigarh publish in Kidney International, an excellent clinical sign- Melanonychia following cyclophosphamide therapy.
Today’s NEJM has an excellent Original Article from Dr Goldstein’s group on Pediatric AKI- the results of the AWARE study. It also has an Editorial on it. This large, prospective, multinational study of the epidemiology of acute kidney injury in children and young adults in ICUs showed that acute kidney injury occurred in one quarter